Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.56 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.56 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | F7 | P08709 | 4/20 | 0.51 |
| ▸ | F3 | P13726 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469664 | 1.00 | KDM4E (0.73) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL16800411 | 0.99 | KDM4E (0.71) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL17369041 | 0.99 | KDM4E (0.71) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL16800410 | 0.97 | KDM4E (0.73) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL8814970 | 0.97 | KDM4E (0.73) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL8814964 | 0.97 | KDM4E (0.73) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL7710665 | 0.96 | KDM4E (0.75) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL454163 | 0.96 | KDM4E (0.75) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL17369039 | 0.96 | KDM4E (0.75) | KDM4EMEN1RECQLKMT2APOLM | |
| SCHEMBL16770314 | 0.91 | KDM4E (0.71) | KDM4EMEN1RECQLKMT2APOLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990164-A | CARDIOVASCULAR DISORDERS, ANTIDIABETIC AGENTS, SKIN DISEASES, ANTIINFLAMMATORY AND -CARCINOGENIC AGENTS, IMMUNOLOGICAL DISEASES, PSYCHOLOGICAL AND SKIN DISORDERS; WATER SOLUBLE; NUTRIENTS; FOODS; TOPICAL | SCOTIA HOLDINGS PLC (GB) | 1999-11-23 | — | — | US | disclosed |