Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31216719 | 1.00 | TRPV1 (0.45) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL31216703 | 1.00 | TRPV1 (0.45) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL17396607 | 1.00 | TRPV1 (0.45) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL6432267 | 0.89 | TRPV1 (0.48) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL5697377 | 0.89 | TRPV1 (0.42) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL31628727 | 0.89 | TRPV1 (0.54) | TRPV1PRKCAFFAR1FFAR4FAAH | |
| SCHEMBL25207146 | 0.89 | TRPV1 (0.48) | TRPV1GLS2PRKCAFFAR1FFAR4 | |
| SCHEMBL830444 | 0.86 | TRPV1 (0.52) | TRPV1PRKCAFFAR1FFAR4FAAH | |
| SCHEMBL7531489 | 0.86 | TRPV1 (0.52) | TRPV1PRKCAFFAR1FFAR4FAAH | |
| SCHEMBL4760055 | 0.84 | MAPT (0.57) | PRKCAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675130-B1 | Process for the preparation of phosphonium salts | SHINETSU CHEMICAL CO (JP) | 1999-12-29 | — | — | EP | disclosed |
| US-5481040-A | REACTING A PHOSPHINE WITH A CHLORIDE IN THE PRESENCE OF AN ALKALI METAL SALT AND A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0675130-A2 | Process for the preparation of phosphonium salts | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |