Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436049 | 1.00 | MEN1 (0.31) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8441266 | 0.93 | — | — | |
| SCHEMBL8437396 | 0.91 | — | — | |
| SCHEMBL8441948 | 0.91 | — | — | |
| SCHEMBL8436479 | 0.88 | — | — | |
| SCHEMBL8437501 | 0.88 | — | — | |
| SCHEMBL8441313 | 0.87 | MEN1 (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8439963 | 0.87 | MEN1 (0.32) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL8441168 | 0.86 | — | — | |
| SCHEMBL8437385 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912374-A | Asymmetrical siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0794187-A1 | Asymmetrical siloxy compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-10 | — | — | EP | disclosed |