Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319655 | 1.00 | LSS (0.63) | LSSKDM4EATMKDM1A | |
| SCHEMBL6319652 | 1.00 | LSS (0.63) | LSSKDM4EATMKDM1A | |
| SCHEMBL8439651 | 1.00 | LSS (0.63) | LSSKDM4EATMKDM1A | |
| SCHEMBL6514517 | 0.87 | LSS (0.49) | LSSKDM4EATMKDM1A | |
| SCHEMBL6407449 | 0.87 | LSS (0.49) | LSSKDM4EATMKDM1A | |
| SCHEMBL6514523 | 0.87 | LSS (0.49) | LSSKDM4EATMKDM1A | |
| SCHEMBL6407451 | 0.87 | LSS (0.49) | LSSKDM4EATMKDM1A | |
| SCHEMBL6407444 | 0.87 | LSS (0.49) | LSSKDM4EATMKDM1A | |
| SCHEMBL11853332 | 0.87 | LSS (0.66) | LSS | |
| SCHEMBL10565764 | 0.86 | LSS (0.61) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990163-A | HYDROXY, EPOXY AND/OR CARBOXY DERIVATIVES OF METHOPRENE; ANTITUMOR,-CARCINOGENIC AND -PROLIFERATIVE AGENTS; SKIN DISORDERS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1999-11-23 | — | — | US | disclosed |
| US-4827004-A | ANTIULCER AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0260551-A2 | Isoprene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-03-23 | — | — | EP | disclosed |