⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17598294 | 0.71 | — | — | |
| SCHEMBL8166162 | 0.64 | — | — | |
| SCHEMBL6013729 | 0.62 | — | — | |
| SCHEMBL3472370 | 0.62 | — | — | |
| SCHEMBL25473367 | 0.59 | — | — | |
| SCHEMBL769014 | 0.59 | — | — | |
| SCHEMBL16125856 | 0.59 | — | — | |
| SCHEMBL3640460 | 0.59 | — | — | |
| SCHEMBL10987530 | 0.59 | — | — | |
| SCHEMBL11431144 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000006573-A1 | ANTIVIRAL ALKYL SUBSTITUTED PURINE DERIVATIVES AND THEIR PREPARATION | Kemijski inštitut (SI) | 2000-02-10 | — | — | WO | claimed |
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | claimed |
| EP-0369409-A1 | Carbocyclic nucleosides and nucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-05-23 | — | — | EP | claimed |
| CN-104072539-B | Double (4 acetaminophenol epoxide) esters of tenofovir and preparation method thereof and its application | 安徽贝克联合制药有限公司 | 2017-03-29 | — | — | CN | disclosed |
| CN-102977146-B | A kind of synthetic method of adenine derivative | XINGHU BIOTECH CO., LTD., ZHAOQING CITY, GUANGDONG PROV. (CN) | 2016-04-20 | — | — | CN | disclosed |
| CN-103038241-B | Crystals of tenofovir disoproxil fumarate | JIANGSU CHIATAI TIANQING PHARMACEUTICAL CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-104072539-A | Tenofovir bis(4-acetaminophenoloxy)ester, and preparation method and application thereof | ANHUI BIOCHEM UNITED PHARMACEUTICAL CO LTD | 2014-10-01 | — | — | CN | disclosed |
| CN-102228464-B | Tenofovir composition | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2013-06-05 | — | — | CN | disclosed |
| CN-102066369-B | Bromo-phenyl substituted thiazolyl dihydropyrimidines | GUANGDONG HEC PHARMACEUTICAL | 2013-05-29 | — | — | CN | disclosed |
| CN-102240297-B | Tenofovir crystals | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-102240296-B | Tenofovir solid | BRIGHTGENE BIO MEDICAL TECHNOLOGY CO LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-1175249-A | 3-aryl-1, 2, 4-triazole derivatives having herbicidal properties | BAYER AG (DE) | 1998-03-04 | — | — | CN | disclosed |
| US-5686629-A | CHEMICAL INTERMEDIATES | GILEAD SCIENCES, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| US-5514798-A | REACTION OF CYCLIC CARBONATE WITH PURINE OR PYRIMIDINE BASE IN SOLVENT AND CRYSTALLIZATION | GILEAD SCIENCES, INC. (US) | 1996-05-07 | — | — | US | disclosed |
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | disclosed |
| EP-0205826-B1 | PHOSPHONYLMETHOXYALKYL ADENINES FOR THE TREATMENT OF VIRUS DISEASES | Stichting REGA V.Z.W. (BE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0369409-A1 | Carbocyclic nucleosides and nucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-05-23 | — | — | EP | disclosed |
| US-4724233-A | VIRICIDES | STICHTING REGA VZW (BE) | 1988-02-09 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |
| EP-0205826-A2 | Phosphonylmethoxyalkyl adenines for the treatment of virus diseases | Stichting REGA V.Z.W. (BE) | 1986-12-30 | — | — | EP | disclosed |