Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438129 | 0.75 | CYP11B1 (0.38) | HCAR2CYP11B1CYP11B2HTT | |
| SCHEMBL335671 | 0.71 | — | — | |
| SCHEMBL989986 | 0.71 | — | — | |
| SCHEMBL30966540 | 0.71 | — | — | |
| SCHEMBL14844098 | 0.71 | — | — | |
| SCHEMBL8444733 | 0.71 | HCAR2 (0.35) | HCAR2CHRNB2CHRNA4CYP11B1CYP11B2 | |
| SCHEMBL8436245 | 0.68 | HCAR2 (0.36) | HCAR2CHRNB2CHRNA4 | |
| SCHEMBL21411402 | 0.68 | CHRM5 (0.52) | — | |
| SCHEMBL15741471 | 0.68 | AHR (0.37) | AHR | |
| SCHEMBL8438588 | 0.68 | HCAR2 (0.36) | HCAR2CHRNB2CHRNA4HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |
| US-5968947-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | ZENECA LIMITED (GB) | 1999-10-19 | — | — | US | disclosed |