Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441204 | 1.00 | IDO1 (0.54) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8439697 | 0.89 | IDO1 (0.49) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8275182 | 0.85 | IDO1 (0.46) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8441599 | 0.85 | IDO1 (0.46) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL30133461 | 0.84 | MEN1 (0.48) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8439504 | 0.84 | MEN1 (0.48) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL21580219 | 0.84 | MEN1 (0.48) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL8441520 | 0.84 | IDO1 (0.42) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL12378825 | 0.84 | IDO1 (0.42) | IDO1MEN1KMT2AMAPK1TDP1 | |
| SCHEMBL16247434 | 0.83 | IDO1 (0.47) | IDO1MEN1KMT2AMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955472-A | INHIBITION OF AMYLOID AGGREGATION IN ANIMALS AND PREVENTION OF ALZHEIMER'S DISEASE | WARNER-LAMBERT COMPANY (US) | 1999-09-21 | — | — | US | claimed |