Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 10/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 6/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443145 | 0.84 | KDM1A (0.50) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL7456133 | 0.77 | MAOB (0.56) | MAOBMAOA | |
| SCHEMBL8013728 | 0.72 | KDM1A (0.39) | KDM1AMAOBMAOA | |
| SCHEMBL8083999 | 0.72 | HIF1A (0.41) | KDM1A | |
| SCHEMBL8083996 | 0.72 | HIF1A (0.41) | KDM1A | |
| SCHEMBL8443676 | 0.71 | F10 (0.42) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL8079209 | 0.71 | HIF1A (0.47) | KDM1AMAOBMAOA | |
| SCHEMBL8079208 | 0.71 | HIF1A (0.47) | KDM1AMAOBMAOA | |
| SCHEMBL10612349 | 0.70 | KDM4E (0.53) | KDM1APTGER4PTGER3PTGER2 | |
| SCHEMBL12971911 | 0.65 | KDM1A (0.58) | HTR2CKDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945557-A | PHENYL DERIVATIVES WHICH POSSESS A SUBSTITUTED CYCLOPROPYL MOIETY; USEFUL AGAINST POWDERY MILDEW, BLIGHT AND OTHER PLATN DISEASES; INSECTICIDES AGAINST SOUTHERN ARMYWORM, MEXICAN BEAN BEETLE AND SPIDER MITES, FOR EXAMPLE | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |