Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | SCN4A | P35499 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.53 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11369212 | 0.99 | KDM4E (0.55) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| Hydrochloric Acid SCHEMBL7768556 | 0.80 | TP53 (0.44) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL10930809 | 0.79 | TP53 (0.46) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| Hydrochloric Acid SCHEMBL11369211 | 0.78 | BCHE (0.42) | — | |
| SCHEMBL10824788 | 0.77 | ITGB2 (0.46) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL10803512 | 0.76 | MAPK1 (0.55) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL10803507 | 0.76 | MAPK1 (0.55) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL7377505 | 0.75 | KDM4E (0.46) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL11820176 | 0.73 | KDM1A (0.59) | KDM4ETP53MAPK1CACNA1SCYP3A4 | |
| SCHEMBL11468421 | 0.72 | KDM1A (0.58) | KDM4ETP53MAPK1CACNA1SCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59106477-A | — | — | None | — | — | JP | disclosed |
| EP-0662321-B1 | Method for producing osmosis-controlled tablets avoiding the use of chlorinated hydrocarbons | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1999-10-20 | — | — | EP | disclosed |
| EP-0662321-A1 | Method for producing osmosis-controlled tablets avoiding the use of chlorinated hydrocarbons | EGIS GYOGYSZERGYAR RT. (HU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0292824-B1 | PROCESS FOR THE NUCLEAR CHLORINATION OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4851596-A | Process for nucleus-chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-25 | — | — | US | disclosed |
| EP-0292824-A1 | Process for the nuclear chlorination of aromatic hydrocarbons | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| JP-S59106477-A | NOVEL 1,5-BENZOTHIAZEPIN DERIVATIVE AND ITS PREPARATION | HAMARI YAKUHIN KOGYO KK | 1984-06-20 | — | — | JP | disclosed |