Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 4/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843834 | 0.91 | CHRNA7 (0.34) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843413 | 0.89 | SMYD3 (0.33) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843928 | 0.87 | CHRNA7 (0.36) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843157 | 0.86 | CHRNA7 (0.35) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843782 | 0.86 | CHRNA7 (0.35) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL844412 | 0.86 | CHRNA7 (0.35) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL842935 | 0.84 | CHRNA7 (0.34) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843792 | 0.84 | CHRNA7 (0.34) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL844322 | 0.84 | CHRNA7 (0.34) | CHRNA7SMYD3HTR3AHTR3EHTR3B | |
| SCHEMBL843219 | 0.84 | CHRNA7 (0.34) | CHRNA7SMYD3HTR3AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432707-B1 | AZABICYCLIC-SUBSTITUTED FUSED-HETEROARYL COMPOUNDS FOR THE TREATMENT OF DISEASE | PHARMACIA & UPJOHN CO LLC (US) | 2012-03-28 | — | — | EP | claimed |