⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329169 | 1.00 | — | — | |
| SCHEMBL8443444 | 1.00 | — | — | |
| SCHEMBL2842548 | 0.97 | — | — | |
| SCHEMBL3818691 | 0.97 | — | — | |
| SCHEMBL7812536 | 0.97 | — | — | |
| SCHEMBL2842549 | 0.97 | — | — | |
| SCHEMBL3818693 | 0.97 | — | — | |
| SCHEMBL27315769 | 0.80 | — | — | |
| SCHEMBL9923470 | 0.77 | — | — | |
| SCHEMBL21297577 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0460940-A1 | Pesticidal 1-arylpyrroles | RHONE-POULENC AGROCHIMIE (FR) | 1991-12-11 | — | — | EP | claimed |
| CN-104334534-B | Improved process for preparing 1-aryl-5-alkylpyrazole compounds | 勃林格殷格翰动物保健美国公司 | 2020-01-10 | — | — | CN | disclosed |
| EP-3184510-B1 | IMPROVED PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS | MERIAL INC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3184510-A1 | IMPROVED PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS | Merial, Inc. (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2852577-B1 | IMPROVED PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS | MERIAL INC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9273007-B2 | Processes for the preparation of 1-aryl-5-alkyl pyrazole compounds | MERIAL, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-20150073153-A1 | PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS | MERIAL LIMITED (US) | 2015-03-12 | — | — | US | disclosed |
| US-8937185-B2 | Processes for the preparation of 1-aryl-5-alkyl pyrazole compounds | MERIAL LIMITED (US) | 2015-01-20 | — | — | US | disclosed |
| US-20130281710-A1 | PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS | MERIAL LIMITED (US) | 2013-10-24 | — | — | US | disclosed |
| EP-0460940-B1 | Pesticidal 1-arylpyrroles | RHONE POULENC AGROCHIMIE (FR) | 1999-01-27 | — | — | EP | disclosed |
| US-5506260-A | INSECTICIDES, ACARICIDES, NEMATOCIDES | RHONE-POULENC AG COMPANY (US) | 1996-04-09 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0460940-A1 | Pesticidal 1-arylpyrroles | RHONE-POULENC AGROCHIMIE (FR) | 1991-12-11 | — | — | EP | disclosed |