SCHEMBL8443532

SCHEMBL8443532

N#Cc1ccc(N(C(c2ccccc2)C(F)(F)F)n2cnnc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 19/20 0.48
OPRD1 P41143 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27661771 0.80 CYP19A1 (0.44) CYP19A1OPRD1
SCHEMBL3236162 0.69 CYP19A1 (0.56) CYP19A1
SCHEMBL3237842 0.69 MAOB (0.56) CYP19A1
SCHEMBL2060207 0.69 CYP19A1 (0.55) CYP19A1
SCHEMBL8443364 0.67 CYP19A1 (0.53) CYP19A1
SCHEMBL8446304 0.66 CYP19A1 (0.75) CYP19A1
SCHEMBL8446297 0.65 CYP19A1 (0.50) CYP19A1
SCHEMBL8443529 0.64 CYP19A1 (0.70) CYP19A1
SCHEMBL8446302 0.60 CYP19A1 (0.86) CYP19A1
SCHEMBL28624125 0.60 CYP19A1 (0.59) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0641785-B1 TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF YAMANOUCHI PHARMA CO LTD (JP) 1999-10-27 EP disclosed
EP-0641785-A1 TRIAZOLYLATED TERTIARY AMINE COMPOUND OR SALT THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1995-03-08 EP disclosed