Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191783 | 1.00 | EPHX1 (0.50) | EPHX1TDP1GRM4PSEN1PSEN2 | |
| SCHEMBL6821952 | 1.00 | EPHX1 (0.50) | EPHX1TDP1GRM4PSEN1PSEN2 | |
| SCHEMBL7899582 | 1.00 | EPHX1 (0.50) | EPHX1TDP1GRM4PSEN1PSEN2 | |
| SCHEMBL7912637 | 0.95 | EPHX1 (0.45) | EPHX1TDP1GRM4PSEN1PSEN2 | |
| SCHEMBL16705043 | 0.80 | EPHX1 (0.48) | EPHX1TDP1GRM4PSEN1PSEN2 | |
| SCHEMBL28117191 | 0.80 | EPHX1 (0.54) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL15774888 | 0.80 | EPHX1 (0.48) | EPHX1GRM4PSEN1PSEN2APH1B | |
| SCHEMBL9376361 | 0.79 | PEPD (0.42) | TDP1PEPD | |
| SCHEMBL7907529 | 0.79 | PEPD (0.42) | TDP1PEPD | |
| SCHEMBL13761134 | 0.79 | PEPD (0.42) | TDP1PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724260-A1 | Process for the synthesis of ¬2S, 3aR, 7aS|-octahydroindole-2-carboxylic acid and its conversion to trandolapril | Sochinaz SA (CH) | 2006-11-22 | — | — | EP | disclosed |