Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | CLK2 | P49760 | 1/20 | 0.71 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373510 | 1.00 | KDM4E (0.71) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| SCHEMBL8445131 | 1.00 | KDM4E (0.71) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| SCHEMBL9373526 | 1.00 | KDM4E (0.71) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| SCHEMBL8445136 | 1.00 | KDM4E (0.71) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9846600 | 0.99 | KDM4E (0.70) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9773763 | 0.99 | KDM4E (0.70) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9846615 | 0.99 | KDM4E (0.70) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9846575 | 0.99 | KDM4E (0.70) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| Hydrochloric Acid SCHEMBL9846579 | 0.99 | KDM4E (0.70) | KDM4EKCNH2ALDH1A1HPGDPOLB | |
| SCHEMBL6168969 | 0.95 | KDM4E (0.69) | KDM4EKCNH2ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | claimed |
| EP-0464823-B1 | (6,7-Substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-O3,O4)bis(acyloxy-O)borates and the salts thereof, and methods for their manufacture | KYORIN SEIYAKU KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0230295-B1 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN SEIYAKU KK (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5157117-A | (6,7)-SUBSTITUTED-8-ALKOXY-1-CYCLOPROPYL-1,4-DIHYDRO-4-OXO-3-QUINOLINECARBOXYLIC ACID-03,04) BIS (ACYLOXY-0) BORATE AND THE SALT THEREOF, AND THE PREPARING METHOD OF THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-10-20 | — | — | US | disclosed |
| EP-0464823-A1 | (6,7-Substituted-8-alkoxy-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid-O3,O4)bis(acyloxy-O)borates and the salts thereof, and methods for their manufacture | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5043450-A | Bactericides | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-4980470-A | 8-alkoxyquinolonecarboxylic acid and salts thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1990-12-25 | — | — | US | disclosed |
| EP-0230295-A2 | 8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-07-29 | — | — | EP | disclosed |