Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.63 |
| ▸ | DPP4 | P27487 | 3/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442123 | 0.94 | ABCG2 (0.64) | ABCG2DPP4PTPN1MAPTNPC1 | |
| SCHEMBL7194183 | 0.87 | SMPD1 (0.54) | ABCG2DPP4PTPN1KEAP1NFE2L2 | |
| SCHEMBL7191866 | 0.87 | ABCG2 (0.67) | ABCG2DPP4PTPN1MAPTSMN1; SMN2 | |
| SCHEMBL7187007 | 0.86 | SMPD1 (0.56) | ABCG2DPP4PTPN1KEAP1NFE2L2 | |
| SCHEMBL7180833 | 0.85 | ABCG2 (0.86) | ABCG2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7180829 | 0.85 | ABCG2 (0.86) | ABCG2MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7192546 | 0.84 | DPP4 (0.54) | ABCG2DPP4PTPN1KEAP1NFE2L2 | |
| SCHEMBL7192543 | 0.84 | DPP4 (0.54) | ABCG2DPP4PTPN1KEAP1NFE2L2 | |
| SCHEMBL1577013 | 0.84 | TYR (0.59) | ABCG2DPP4PTPN1BCHEACHE | |
| SCHEMBL1577012 | 0.84 | TYR (0.59) | ABCG2DPP4PTPN1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |