SCHEMBL8445316

SCHEMBL8445316

CC(F)(F)C(O)=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518123 0.74
SCHEMBL1681777 0.73
SCHEMBL1196753 0.73
SCHEMBL9356543 0.72
SCHEMBL8983011 0.72
SCHEMBL3890037 0.72
SCHEMBL350243 0.70
SCHEMBL28291376 0.70
SCHEMBL1524778 0.70
SCHEMBL10343112 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813644-A Preparation method of flomoxef mother nucleus 广东立国制药有限公司 2023-09-29 CN claimed
US-4491547-A Fluoromethylthioacetic acid compounds SHIONOGI & CO., LTD. (JP) 1985-01-01 US claimed
JP-57109761-A None JP disclosed
CN-117124409-A Preparation method of corrosion-resistant high-antibacterial-property plywood 江西红锦发木业有限公司 2023-11-28 CN disclosed
CN-116901193-A Preparation method of corrosion-resistant high-toughness plywood 江西红锦发木业有限公司 2023-10-20 CN disclosed
CN-116813644-A Preparation method of flomoxef mother nucleus 广东立国制药有限公司 2023-09-29 CN disclosed
CN-116813644-A Preparation method of flomoxef mother nucleus 广东立国制药有限公司 2023-09-29 CN disclosed
EP-3778577-B1 NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY LG CHEMICAL LTD (KR) 2023-08-30 EP disclosed
CN-116514841-A Preparation method of flomoxef acid impurity 福建省福抗药业股份有限公司 2023-08-01 CN disclosed
CN-109485659-B Process for preparing 7 alpha-alkoxyoxycephalosporane intermediates 东都股份有限公司 2021-09-10 CN disclosed
CN-111646930-A Preparation method of flomoxef 7-site side chain 山西千岫制药有限公司 2020-09-11 CN disclosed
CN-1034504-C Thioalkylthio cephalosporin derivatives SHIONOGI & CO (JP) 1997-04-09 CN disclosed
US-5352792-A Bactericides SHIONOGI & CO., LTD. (JP) 1994-10-04 US disclosed
EP-0467647-B1 Thioalkylthio cephalosporin derivatives SHIONOGI & CO (JP) 1994-08-17 EP disclosed
EP-0594263-A1 Thioalkylthio cephalosporin derivatives and intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1994-04-27 EP disclosed
US-5214037-A Antibiotic, bactericide SHIONOGI & CO., LTD. (JP) 1993-05-25 US disclosed
EP-0467647-A2 Thioalkylthio cephalosporin derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1992-01-22 EP disclosed
US-4491547-A Fluoromethylthioacetic acid compounds SHIONOGI & CO., LTD. (JP) 1985-01-01 US disclosed
US-4491547-A Fluoromethylthioacetic acid compounds SHIONOGI & CO., LTD. (JP) 1985-01-01 US disclosed
JP-S57109761-A FLUOROMETHYLTHIOACETIC ACID COMPOUND AND ITS PREPARATION SHIONOGI & CO LTD 1982-07-08 JP disclosed