Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442855 | 1.00 | GRM1 (0.30) | GRM1 | |
| SCHEMBL8444783 | 0.93 | — | — | |
| SCHEMBL7837000 | 0.91 | BDKRB1 (0.32) | — | |
| SCHEMBL7826294 | 0.91 | BDKRB1 (0.31) | — | |
| SCHEMBL7834927 | 0.91 | BDKRB1 (0.31) | — | |
| SCHEMBL8444556 | 0.91 | GRM1 (0.30) | GRM1 | |
| SCHEMBL8444754 | 0.91 | GRM1 (0.30) | GRM1 | |
| SCHEMBL7837429 | 0.90 | BDKRB1 (0.32) | — | |
| SCHEMBL7836984 | 0.89 | — | — | |
| SCHEMBL7834118 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915845-A1 | ACRYLOYL SUBSTITUTED DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004524-A1 | ACRYLOYL SUBSTITUTED DISTAMYCIN DERIVATIVES, PROCESS FOR PREPARING THEM, AND THEIR USE AS ANTITUMOR AND ANTIVIRAL AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-02-05 | — | — | WO | disclosed |