Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445985 | 1.00 | F7 (0.39) | F7PARP1F3PARP10CYP19A1 | |
| SCHEMBL8445984 | 1.00 | F7 (0.39) | F7PARP1F3PARP10CYP19A1 | |
| SCHEMBL9395184 | 0.88 | SRD5A1 (0.48) | CYP19A1CYP11B1CYP11B2SRD5A1SRD5A2 | |
| SCHEMBL9395181 | 0.88 | SRD5A1 (0.48) | CYP19A1CYP11B1CYP11B2SRD5A1SRD5A2 | |
| SCHEMBL9395179 | 0.88 | SRD5A1 (0.48) | CYP19A1CYP11B1CYP11B2SRD5A1SRD5A2 | |
| SCHEMBL8138357 | 0.82 | PARP1 (0.39) | PARP1PARP10CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8138355 | 0.82 | PARP1 (0.39) | PARP1PARP10CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6755935 | 0.82 | TDP1 (0.42) | PARP1PARP10CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6755932 | 0.82 | TDP1 (0.42) | PARP1PARP10CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6755934 | 0.82 | TDP1 (0.42) | PARP1PARP10CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | claimed |
| EP-0759025-B1 | AMIDE DERIVATIVES AND THEIR THERAPEUTIC USE | WELLCOME FOUND (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5719186-A | CENTRAL MUSCLE RELAXANTS, ANXIOLYTIC AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTICONVULSANTS | GLAXO WELLCOME INC. (US) | 1998-02-17 | — | — | US | disclosed |
| WO-1994026692-A1 | BICYCLIC AMIDE DERIVATIVES AND THEIR USE AS MUSCLE RELAXANTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-11-24 | — | — | WO | disclosed |