SCHEMBL8446409 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	9/20	0.60

▸	ACE	P12821	7/20	0.60

▸	CTSB	P07858	1/20	0.45

▸	MEN1	O00255	1/20	0.44

▸	KMT2A	Q03164	1/20	0.44

▸	TACR1	P25103	1/20	0.43

▸	ACE2	Q9BYF1	3/20	0.43

▸	MBTPS1	Q14703	1/20	0.42

▸	POLB	P06746	1/20	0.42

▸	CPA1	P15085	2/20	0.42

▸	ANPEP	P15144	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8449902	0.94	MME (0.58)	MMEACECTSBMEN1KMT2A
SCHEMBL8447177	0.94	MME (0.62)	MMEACECTSBMEN1KMT2A
SCHEMBL8448662	0.93	MME (0.57)	MMEACECTSBMEN1KMT2A
SCHEMBL8452877	0.93	MME (0.56)	MMEACECTSBMEN1KMT2A
SCHEMBL8453062	0.92	MME (0.56)	MMEACECTSBMEN1KMT2A
SCHEMBL8452236	0.90	MME (0.53)	MMEACECTSB
SCHEMBL8447122	0.89	MME (0.57)	MMEACECTSBMEN1KMT2A
SCHEMBL8450243	0.89	MME (0.57)	MMEACECTSBMEN1KMT2A
SCHEMBL7567309	0.89	MME (0.76)	MMEACEACE2CPA1
SCHEMBL7568195	0.89	MME (0.76)	MMEACEACE2CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5968980-A	ENDOPEPTIDASE 24.11 INHIBITORS	SANTEN PHARMACEUTICAL CO., LTD. (JP)	1999-10-19	—	—	US	disclosed