SCHEMBL8446594

SCHEMBL8446594

CN(C)c1ccc(CSCC(NC(=O)CCS)C(=O)O)cc1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACE P12821 17/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8450293 0.93 ACE (0.67) ACE
SCHEMBL8446642 0.91 ACE (0.65) ACE
SCHEMBL20734772 0.85 ACE (0.69) ACE
SCHEMBL6576191 0.82 ACE (1.00) ACE
SCHEMBL8447630 0.82 ACE (0.69) ACE
SCHEMBL10004544 0.82 ACE (1.00) ACE
SCHEMBL2108008 0.82 ACE (1.00) ACE
SCHEMBL4565424 0.82 ACE (1.00) ACE
SCHEMBL6575388 0.79 ACE (0.73) ACE
SCHEMBL6575392 0.79 ACE (0.73) ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5872281-A COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION SANTEN PHARMACEUTICAL CO., LTD. (JP) 1999-02-16 US disclosed