Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921467 | 0.93 | SSTR4 (0.43) | NPC1RAB9AMAPTGAAHDAC1 | |
| SCHEMBL22772342 | 0.85 | ESR1 (0.48) | MAPTTSHRALDH1A1GAAHPGD | |
| SCHEMBL8351698 | 0.85 | ACACB (0.49) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL935057 | 0.84 | SSTR4 (0.53) | MAPTGAAHDAC1HDAC6SSTR4 | |
| SCHEMBL18740446 | 0.83 | POLB (0.50) | NPC1RAB9AMAPTTSHRSMN1; SMN2 | |
| SCHEMBL1933209 | 0.83 | PDE2A (0.46) | NPC1RAB9AALDH1A1HDAC1SMN1; SMN2 | |
| SCHEMBL2884007 | 0.83 | TPMT (0.40) | NPC1RAB9AMAPTHDAC1KIF11 | |
| SCHEMBL529254 | 0.83 | EPHX2 (0.42) | NPC1RAB9AMAPTALDH1A1HPGD | |
| SCHEMBL9971091 | 0.83 | NPC1 (0.46) | NPC1RAB9AMAPTTSHRALDH1A1 | |
| SCHEMBL9120395 | 0.83 | TSHR (0.52) | NPC1RAB9AMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080383-A2 | PERSONAL CARE COMPOSITIONS INCLUDING AQUEOUS COMPOSITIONS OF VISCOELASTIC SURFACTANTS AND HYDROPHOBICALLY MODIFIED POLYMERS | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2012-06-21 | — | — | WO | disclosed |
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |