SCHEMBL8447

SCHEMBL8447

c1ccc2c(c1)CCCO2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB2 P05107 1/20 0.52
ICAM1 P05362 1/20 0.52
ITGAL P20701 1/20 0.52
TSHR P16473 1/20 0.48
CTNNB1 P35222 7/20 0.46
WNT3A P56704 7/20 0.46
LMNA P02545 2/20 0.46
CRHBP P24387 2/20 0.46
CRHR2 Q13324 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 1/20 0.46
CLK1 P49759 1/20 0.44
DYRK1A Q13627 1/20 0.44
DYRK1B Q9Y463 1/20 0.44
OXTR P30559 1/20 0.43
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.40
NOTUM Q6P988 1/20 0.38
RIPK1 Q13546 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL28202465 1.00 ITGB2 (0.52) ITGB2ICAM1ITGALTSHRCTNNB1
SCHEMBL5313090 1.00 ITGB2 (0.52) ITGB2ICAM1ITGALTSHRCTNNB1
SCHEMBL28007596 1.00 ITGB2 (0.52) ITGB2ICAM1ITGALTSHRCTNNB1
SCHEMBL29356442 1.00 ITGB2 (0.52) ITGB2ICAM1ITGALTSHRCTNNB1
Water SCHEMBL7527071 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1
SCHEMBL7650589 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1
Water SCHEMBL5189676 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1
Ammonia Solution, Strong SCHEMBL2078097 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1
Bromide SCHEMBL11373619 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1
Iodide SCHEMBL30543385 0.98 ITGB2 (0.50) ITGB2ICAM1ITGALTSHRCTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26595 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6362369-B1 None US claimed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP claimed
CN-122079323-A Controlled release type polymeric ferric sulfate water treatment agent and preparation method thereof 2026-05-26 CN claimed
CN-122059918-A Synthesis method and application of cyclobutane chroman skeleton molecular compound 昆明理工大学 2026-05-19 CN claimed
CN-120866196-B Serum-free embryo cutting biopsy culture solution and application thereof 中国农业大学 2026-05-15 CN claimed
US-12606510-B2 Phenol recovery of bisphenol-A mother liquor purge using purification train in the phenol production unit SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-04-21 US claimed
EP-3768675-B1 NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME YUHAN CORP (KR) 2026-04-01 EP claimed
EP-4188379-B1 POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PREVENTING INFLUENZA MERCK SHARP & DOHME LLC (US) 2026-02-25 EP claimed
EP-3786216-B1 PROCESSING ADDITIVES AND USES OF SAME IN ROTATIONAL MOLDING CYTEC TECH CORP (US) 2026-02-11 EP claimed
EP-4678634-A1 ANDROGEN RECEPTOR MODULATORS AND USES THEREOF Haihe Biopharma Co., Ltd. (CN) 2026-01-14 EP claimed
US-4199361-A 3-ANILINO-5-PYRAZOLONE MAGENTA COLOR-FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-04-22 US claimed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-4165985-A PHOTOCONDUCTIVE, HETEROCYCLIC-SUBSTITUTED ISOQUINOLINE COLORANTS EASTMAN KODAK COMPANY (US) 1979-08-28 US claimed
US-4145215-A PHOTOCONDUCTIVE PIGMENTS EASTMAN KODAK COMPANY (US) 1979-03-20 US claimed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
EP-0000596-A1 Electrically photosensitive particles for electrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
US-4138259-A Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1979-02-06 US claimed
US-4119643-A HYPOTENSIVE AGENTS BEECHAM GROUP LIMITED (GB) 1978-10-10 US claimed
US-4015990-A TOCOPHEROL DERIVATIVE AS STABILIZER MITSUBISHI PAPER MILLS, LTD. (JA) 1977-04-05 US claimed