Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HBB | P68871 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.66 |
| ▸ | HPRT1 | P00492 | 12/20 | 0.55 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711558 | 1.00 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL711557 | 1.00 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL711556 | 1.00 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL7745036 | 0.93 | PDE3A (0.71) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL14595282 | 0.93 | MEN1 (0.68) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL708704 | 0.93 | PDE3A (0.68) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL7077795 | 0.93 | PDE3A (0.68) | MEN1KMT2AHBBMAPK1PDE3A | |
| Valomaciclovir SCHEMBL711293 | 0.93 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| Valomaciclovir SCHEMBL417653 | 0.93 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL708703 | 0.93 | PDE3A (0.68) | MEN1KMT2AHBBMAPK1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888348-A1 | ACYCLIC NUCLEOSIDE DERIVATIVES | Medivir Aktiebolag (SE) | 1999-01-07 | — | — | EP | disclosed |
| EP-0880521-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDES | Medivir Aktiebolag (SE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997030052-A1 | SYNTHESIS OF ACYCLIC NUCLEOSIDES | MEDIVIR AB (SE) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997030051-A1 | ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 1997-08-21 | — | — | WO | disclosed |