Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575444 | 0.92 | ACE (0.70) | ACE | |
| SCHEMBL6574200 | 0.92 | ACE (0.70) | ACE | |
| SCHEMBL6574206 | 0.92 | ACE (0.70) | ACE | |
| SCHEMBL6575447 | 0.92 | ACE (0.70) | ACE | |
| SCHEMBL8451676 | 0.90 | ACE (0.56) | ACE | |
| SCHEMBL5695616 | 0.89 | ACE (0.57) | ACEMMP1FCER2 | |
| SCHEMBL8452662 | 0.85 | ACE (0.58) | ACE | |
| SCHEMBL6576380 | 0.84 | ACE (0.59) | ACE | |
| SCHEMBL8447318 | 0.84 | ACE (0.59) | ACE | |
| SCHEMBL6576378 | 0.84 | ACE (0.59) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872281-A | COMPOUNDS FOR TREATMENT OF RHEUMATIC DISEASES, PSORIASIS, INTESTINAL INFLAMATION | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |