Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 7/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.45 |
| ▸ | POLG | P54098 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819447 | 0.91 | MEN1 (1.00) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9021892 | 0.89 | TSHR (0.81) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL8444939 | 0.86 | MEN1 (0.80) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL9022143 | 0.84 | KMT2A (0.62) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL1177579 | 0.84 | MEN1 (0.68) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL8445568 | 0.83 | MEN1 (0.73) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL1178400 | 0.82 | MEN1 (0.65) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL1177567 | 0.81 | MEN1 (0.64) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL14383601 | 0.81 | TSHR (0.72) | MEN1KMT2ATSHRHBBMAPK1 | |
| SCHEMBL8522343 | 0.80 | MEN1 (0.70) | MEN1KMT2ATSHRHBBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704445-B1 | Preparation of N-9 substituted guanine compounds | HOFFMANN LA ROCHE (CH) | 1999-04-21 | — | — | EP | disclosed |
| EP-0704445-A1 | Preparation of N-9 substituted guanine compounds | F. Hoffmann-La Roche AG (CH) | 1996-04-03 | — | — | EP | disclosed |