SCHEMBL8447668

SCHEMBL8447668

C/C=C/CC[C@H]1CC[C@H](CCc2cc(F)c(C(F)(F)F)c(F)c2)CC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8446852 0.96 DAO (0.33) DAO
SCHEMBL8449963 0.92 DAO (0.34) DAO
SCHEMBL8454804 0.91 DAO (0.33) DAO
SCHEMBL8450269 0.89 DAO (0.35) DAO
SCHEMBL8451711 0.89 DAO (0.32) DAO
SCHEMBL8451068 0.88 DAO (0.35) DAOMAOB
SCHEMBL8453208 0.88 DAO (0.35) DAOMAOB
SCHEMBL8450984 0.87 DAO (0.32) DAO
SCHEMBL8454675 0.87 MAOB (0.32) MAOB
SCHEMBL8451831 0.85 DAO (0.33) DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0647696-B1 Cyclohexane derivative CHISSO CORP (JP) 1999-04-21 EP disclosed
EP-0647696-A1 Cyclohexane derivative Chisso Corporation (JP) 1995-04-12 EP disclosed
US-5382379-A Cyclohexane derivative CHISSO CORPORATION (JP) 1995-01-17 US disclosed