Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448019 | 0.96 | GRIA1 (0.39) | HRH3HRH2HRH1KCNH2GRIA1 | |
| SCHEMBL8447919 | 0.92 | ESR2 (0.37) | HRH3HRH2HRH1GRIA1GRIA2 | |
| SCHEMBL8452719 | 0.92 | GRIA1 (0.37) | HRH3HRH2HRH1KCNH2GRIA1 | |
| SCHEMBL9476513 | 0.88 | HRH3 (0.40) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL9476521 | 0.88 | HRH3 (0.40) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL9476530 | 0.88 | HRH3 (0.40) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL9476502 | 0.88 | HRH3 (0.40) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL8453236 | 0.87 | HRH3 (0.37) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL8453229 | 0.87 | HRH3 (0.37) | HRH3HRH2HRH1KCNH2KIF11 | |
| SCHEMBL8453233 | 0.87 | HRH3 (0.37) | HRH3HRH2HRH1KCNH2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |