Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448424 | 1.00 | MAPT (0.35) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8448422 | 1.00 | MAPT (0.35) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8448230 | 1.00 | MAPT (0.35) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8448420 | 1.00 | MAPT (0.35) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8448234 | 1.00 | MAPT (0.35) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8447516 | 0.99 | CYP11B1 (0.36) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8447520 | 0.99 | CYP11B1 (0.36) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8447517 | 0.99 | CYP11B1 (0.36) | MAPTGAACYP11B1CYP11B2CYP2C9 | |
| SCHEMBL8452645 | 0.96 | CYP11B1 (0.36) | MAPTCYP11B1CYP11B2CYP2C9CYP3A4 | |
| SCHEMBL8452638 | 0.96 | CYP11B1 (0.36) | MAPTCYP11B1CYP11B2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |