Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448297 | 1.00 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8454135 | 0.92 | MAOB (0.45) | MAOBSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL8454128 | 0.92 | MAOB (0.45) | MAOBSLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL8453846 | 0.92 | MAOB (0.34) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8453841 | 0.92 | MAOB (0.34) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8447276 | 0.91 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8447277 | 0.91 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8452008 | 0.90 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8452002 | 0.90 | MAOB (0.40) | MAOBHTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL8452057 | 0.90 | HTR2A (0.35) | MAOBHTR2AHTR2CSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |