Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448314 | 1.00 | SPHK1 (0.47) | SPHK1SPHK2CYP2C9S1PR2S1PR4 | |
| SCHEMBL8452215 | 0.99 | SPHK1 (0.49) | SPHK1SPHK2S1PR2S1PR4S1PR1 | |
| SCHEMBL8452175 | 0.99 | SPHK1 (0.49) | SPHK1SPHK2S1PR2S1PR4S1PR1 | |
| SCHEMBL8452178 | 0.99 | SPHK1 (0.49) | SPHK1SPHK2S1PR2S1PR4S1PR1 | |
| SCHEMBL8452219 | 0.99 | SPHK1 (0.49) | SPHK1SPHK2S1PR2S1PR4S1PR1 | |
| SCHEMBL8448642 | 0.97 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8448638 | 0.97 | SPHK1 (0.43) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8447492 | 0.96 | SPHK1 (0.51) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8447497 | 0.96 | SPHK1 (0.51) | SPHK1SPHK2CYP2C9ALDH1A1LMNA | |
| SCHEMBL8448570 | 0.95 | SPHK1 (0.53) | SPHK1SPHK2S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |