Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551963 | 0.78 | TDP1 (0.59) | TDP1KMT2AMEN1TTRALB | |
| SCHEMBL31094807 | 0.77 | TDP1 (0.42) | TDP1KMT2AMAPTCA12CA9 | |
| SCHEMBL29488320 | 0.76 | TSHR (0.53) | TDP1KMT2AMEN1THRBALDH1A1 | |
| SCHEMBL505223 | 0.76 | TSHR (0.53) | TDP1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3910666 | 0.76 | TSHR (0.53) | TDP1KMT2AMEN1THRBALDH1A1 | |
| SCHEMBL4964293 | 0.75 | TDP1 (0.52) | TDP1KMT2AMEN1TTRALB | |
| SCHEMBL8335528 | 0.75 | TDP1 (0.52) | TDP1KMT2AMEN1TTRALB | |
| Hydrochloric Acid SCHEMBL7423303 | 0.75 | TSHR (0.51) | TDP1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10964869 | 0.74 | KMT2A (0.37) | KMT2AATMTSHRMAPK1CYP3A4 | |
| SCHEMBL10727741 | 0.74 | TDP1 (0.67) | TDP1KMT2AMEN1TTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656202-B1 | Dyeing composition containing sulphurous p-phenylene-diamines, sulphurous p-phenylenediamines and method of preparation | OREAL (FR) | 1999-05-06 | — | — | EP | disclosed |
| EP-0656202-A1 | Dyeing composition containing sulphurous p-phenylene-diamines, novel sulphurous p-phenylenediamines and method of preparation | L'OREAL (FR) | 1995-06-07 | — | — | EP | disclosed |