Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.63 |
| ▸ | ACE | P12821 | 12/20 | 0.63 |
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8455768 | 0.92 | MME (0.53) | MMEACEUTS2R | |
| SCHEMBL8447805 | 0.91 | MME (0.52) | MMEACEUTS2RMMP9 | |
| SCHEMBL8447801 | 0.90 | MME (0.52) | MMEACEUTS2R | |
| SCHEMBL8448729 | 0.88 | MME (0.52) | MMEACEUTS2R | |
| SCHEMBL8447368 | 0.88 | MME (0.58) | MMEACE | |
| SCHEMBL8448427 | 0.86 | MME (0.48) | MMEACEUTS2R | |
| SCHEMBL8455345 | 0.86 | ACE (0.46) | MMEACEUTS2RMMP9 | |
| SCHEMBL8448622 | 0.86 | POLB (0.48) | MMEACEUTS2R | |
| SCHEMBL8447359 | 0.86 | UTS2R (0.47) | MMEACEUTS2R | |
| SCHEMBL8448677 | 0.85 | MME (0.47) | MMEACEMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | claimed |
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |