SCHEMBL8448583

SCHEMBL8448583

CCC[C@H]1CC[C@H](CCC2CCC(c3ccccc3)CC2)CC1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.57
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
MAPT P10636 1/20 0.54
MEN1 O00255 1/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 1/20 0.54
DRD2 P14416 2/20 0.51
KDM4E B2RXH2 1/20 0.45
ESR2 Q92731 1/20 0.44
SLC18A3 Q16572 2/20 0.44
SIGMAR1 Q99720 1/20 0.44
DRD1 P21728 1/20 0.44
DRD4 P21917 1/20 0.44
DRD5 P21918 1/20 0.44
DRD3 P35462 1/20 0.44
IDO1 P14902 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8448585 1.00 CYP2C9 (0.57) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8448582 1.00 CYP2C9 (0.57) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL548537 0.98 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL1790467 0.98 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL548536 0.98 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8527560 0.93 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8735498 0.93 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8735502 0.93 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8735500 0.93 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8527556 0.93 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858275-A Chlorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0785179-A1 CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1997-07-23 EP disclosed