SCHEMBL8449378

SCHEMBL8449378

COCCCCC[SiH]1CCC(c2cc(F)c(-c3ccc(OCC(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8449383 1.00 PRMT5 (0.30) PRMT5
SCHEMBL8449046 0.91 KDM1A (0.33)
SCHEMBL8449049 0.91 KDM1A (0.33)
SCHEMBL8451931 0.81 KDM1A (0.37)
SCHEMBL8451932 0.81 KDM1A (0.37)
SCHEMBL8727389 0.78
SCHEMBL8727387 0.78
SCHEMBL8727385 0.78
SCHEMBL8454722 0.77 KDM1A (0.34)
SCHEMBL8454725 0.77 KDM1A (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004478-A LIQUID CRYSTAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-12-21 US disclosed
EP-0732335-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-09-18 EP disclosed