Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29268145 | 0.83 | CYP2C19 (0.56) | KDM4EALDH1A1TSHRHDAC1HDAC2 | |
| SCHEMBL4086630 | 0.73 | — | — | |
| SCHEMBL8384934 | 0.69 | — | — | |
| SCHEMBL11300802 | 0.67 | APP (0.48) | ALDH1A1HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL11300795 | 0.67 | APP (0.48) | ALDH1A1HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL5704548 | 0.67 | — | — | |
| SCHEMBL5704559 | 0.67 | — | — | |
| SCHEMBL4031821 | 0.66 | MEN1 (0.46) | KDM4EUSP2ALDH1A1TSHRMEN1 | |
| SCHEMBL4031823 | 0.66 | MEN1 (0.46) | KDM4EUSP2ALDH1A1TSHRMEN1 | |
| SCHEMBL10646652 | 0.65 | HCAR2 (0.41) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942909-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998022463-A1 | BICYCLIC AMINE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-28 | — | — | WO | disclosed |