Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449659 | 1.00 | SERPINE1 (0.40) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8449665 | 1.00 | SERPINE1 (0.40) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8449668 | 1.00 | SERPINE1 (0.40) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8457171 | 0.92 | SERPINE1 (0.38) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8457164 | 0.92 | SERPINE1 (0.38) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8457166 | 0.92 | SERPINE1 (0.38) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8457174 | 0.92 | SERPINE1 (0.38) | SERPINE1PLA2G7SSTR3HSD11B1KMT2A | |
| SCHEMBL8457947 | 0.87 | SCN1A (0.39) | SERPINE1KMT2AF2PRSS1PRSS2 | |
| SCHEMBL8457945 | 0.87 | SCN1A (0.39) | SERPINE1KMT2AF2PRSS1PRSS2 | |
| SCHEMBL8457933 | 0.87 | SCN1A (0.39) | SERPINE1KMT2AF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |