Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.56 |
| ▸ | ACE | P12821 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450800 | 0.93 | MME (0.59) | MMEACEPOLBMEN1KMT2A | |
| SCHEMBL7568968 | 0.92 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7568973 | 0.92 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7572261 | 0.89 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7572256 | 0.89 | MME (0.66) | MMEACECTSB | |
| SCHEMBL8451282 | 0.89 | MME (0.58) | MMEACEPOLBMEN1KMT2A | |
| SCHEMBL8447085 | 0.88 | MME (0.51) | MMEACEPOLBMEN1KMT2A | |
| SCHEMBL8446470 | 0.88 | ACE (0.57) | MMEACEPOLBMEN1KMT2A | |
| SCHEMBL8446404 | 0.87 | MME (0.59) | MMEACEPOLBMEN1KMT2A | |
| SCHEMBL8453062 | 0.87 | MME (0.56) | MMEACEPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |