Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.54 |
| ▸ | ACE | P12821 | 6/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567870 | 0.95 | MME (0.61) | MMEACEHDAC1HDAC6CTSB | |
| SCHEMBL8453146 | 0.93 | MME (0.62) | MMEACECTSBTACR1PTPN1 | |
| SCHEMBL8451194 | 0.93 | MME (0.57) | MMEACEHDAC1HDAC6CTSB | |
| SCHEMBL8452063 | 0.93 | MME (0.57) | MMEACEHDAC1HDAC6CTSB | |
| SCHEMBL27464916 | 0.89 | MME (0.63) | MMEACEHDAC1HDAC6CTSB | |
| SCHEMBL8450117 | 0.89 | MME (0.48) | MMEACECTSBTACR1MBTPS1 | |
| SCHEMBL8446447 | 0.89 | MME (0.59) | MMEACECTSBTACR1CTSL | |
| SCHEMBL8452065 | 0.88 | MME (0.54) | MMEACEHDAC1HDAC6CTSB | |
| SCHEMBL8446430 | 0.88 | MME (0.52) | MMEACECTSBTACR1MBTPS1 | |
| SCHEMBL8446424 | 0.88 | MME (0.54) | MMEACEHDAC1HDAC6CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |