Methionine

Methionine

SCHEMBL8450225

CSCC[C@H](N)C(=O)O.N[C@@H](CCS)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.55
SLC7A11 Q9UPY5 1/20 0.55
RNPEP Q9H4A4 1/20 0.47
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
BHMT Q93088 10/20 0.45
BHMT2 Q9H2M3 1/20 0.45
FNTA P49354 2/20 0.44
FNTB P49356 2/20 0.44
PGGT1B P53609 1/20 0.44
NOS2 P35228 2/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL8450224 1.00 PTGS1 (0.55) PTGS1SLC7A11RNPEPANPEPENPEP
Racemethionine SCHEMBL4623089 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Methionine SCHEMBL12096907 0.95 RNPEP (0.52) PTGS1SLC7A11RNPEPANPEPENPEP
Racemethionine SCHEMBL28318256 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Methionine SCHEMBL1610240 0.95 RNPEP (0.52) PTGS1SLC7A11RNPEPANPEPENPEP
Racemethionine SCHEMBL23924425 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Racemethionine SCHEMBL561474 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Methionine SCHEMBL4623092 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Methionine SCHEMBL6157104 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP
Methionine SCHEMBL440066 0.95 PTGS1 (0.61) PTGS1SLC7A11RNPEPANPEPENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0451760-B1 Nitrato alkanoic acid derivatives and method for their production SANOL ARZNEI SCHWARZ GMBH (DE) 1995-09-13 EP claimed
EP-0932689-A1 HOMOCYSTEINE DESULPHURASE FROM THE PROTOZOAN TRICHOMONAS VAGINALIS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 1999-08-04 EP disclosed
WO-1998007872-A1 HOMOCYSTEINE DESULPHURASE FROM THE PROTOZOAN TRICHOMONAS VAGINALIS THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 1998-02-26 WO disclosed