Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450425 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450423 | 1.00 | KDM4E (0.35) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450451 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450454 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450445 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450386 | 0.92 | KDM4E (0.35) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8450381 | 0.92 | KDM4E (0.35) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8448634 | 0.90 | CYP2C9 (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8448626 | 0.90 | CYP2C9 (0.38) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL8456687 | 0.90 | SPHK1 (0.39) | SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0820983-A1 | ACRYLONITRILE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-01-28 | — | — | EP | disclosed |