Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783079 | 0.80 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL3257572 | 0.80 | NPC1 (0.64) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL9394256 | 0.80 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL229329 | 0.80 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL229328 | 0.80 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL31560044 | 0.80 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL28755153 | 0.78 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AATM | |
| 2-Pyridinecarboxaldehyde SCHEMBL29396810 | 0.78 | — | — | |
| 2-Pyridinecarboxaldehyde SCHEMBL55278 | 0.78 | — | — | |
| 2-Pyridinecarboxaldehyde SCHEMBL6943571 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990269-A | FOR USE AS A PHOTORESIST IN THE MANUFACTURE OF BLACK MATRICES AS ON COLOR CRTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5725978-A | SUBSTITUTED DIACETONEACRYLAMIDE POLYMER, VINYLPYRROLIDONE POLYMER | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-10 | — | — | US | disclosed |
| US-4272620-A | Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-06-09 | — | — | US | disclosed |