Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.61 |
| ▸ | ACE | P12821 | 11/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573782 | 0.95 | MME (0.68) | MMEACETACR1CTSBCTSL | |
| SCHEMBL7573777 | 0.95 | MME (0.68) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8450800 | 0.89 | MME (0.59) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL27489674 | 0.86 | MME (0.68) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8453146 | 0.86 | MME (0.62) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8446481 | 0.85 | MME (0.62) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8032641 | 0.85 | MME (0.81) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8016985 | 0.85 | MME (0.81) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8026927 | 0.85 | MME (0.81) | MMEACETACR1CTSBCTSL | |
| SCHEMBL8027177 | 0.85 | MME (0.81) | MMEACETACR1CTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |