SCHEMBL8450878

SCHEMBL8450878

CCCCCCOC1(C#N)C=CC(c2ccccc2)=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 3/20 0.36
NR5A2 O00482 2/20 0.34
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SOAT1 P35610 1/20 0.33
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
CHRM2 P08172 5/20 0.32
CHRM4 P08173 5/20 0.32
CHRM5 P08912 5/20 0.32
CHRM1 P11229 5/20 0.32
CHRM3 P20309 5/20 0.32
PTPN1 P18031 1/20 0.32
LTA4H P09960 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28990415 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL8451920 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL9300431 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL5309651 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL29137832 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL28990417 1.00 NR5A1 (0.36) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL3480934 0.99 NR5A1 (0.34) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL25187775 0.98 NR5A1 (0.35) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL29236280 0.98 NR5A1 (0.35) NR5A1NR5A2CYP2C9CYP2C19MEN1
SCHEMBL29137839 0.98 NR5A1 (0.35) NR5A1NR5A2CYP2C9CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118169925-A Continuous electrochromic polymer stabilized cholesteric liquid crystal material and preparation method thereof 大连理工大学 2024-06-11 CN claimed
CN-113296310-A Quantum dot light conversion layer and preparation method thereof 广东普加福光电科技有限公司 2021-08-24 CN claimed
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
CN-118169925-A Continuous electrochromic polymer stabilized cholesteric liquid crystal material and preparation method thereof 大连理工大学 2024-06-11 CN disclosed
CN-111139117-B Lubricant composition containing an anti-flaking agent 协同油脂株式会社 2023-03-24 CN disclosed
CN-112469388-B Release agent for polymer compound, adhesive material, and method for using adhesive material 国立研究开发法人产业技术综合研究所 2023-03-14 CN disclosed
WO-2023005682-A1 METHOD FOR ANALYZING TARGETED EXPOSURE GROUP OF ENVIRONMENTAL POLLUTANTS IN PLASMA, AND USE THEREOF 暨南大学 2023-02-02 WO disclosed
CN-113296310-A Quantum dot light conversion layer and preparation method thereof 广东普加福光电科技有限公司 2021-08-24 CN disclosed
CN-112469388-A Release agent for polymer compound, adhesive material, and method for using adhesive material 国立研究开发法人产业技术综合研究所 2021-03-09 CN disclosed
CN-111139117-A Anti-flaking agent and lubricant composition containing same 协同油脂株式会社 2020-05-12 CN disclosed
CN-104460037-B The method and apparatus of Ophthalmoligic instrument including cycloid aligned liquid-crystal layer 庄臣及庄臣视力保护公司 2018-09-28 CN disclosed
CN-107964064-A The manufacture method of actuator, liquid crystal elastic body and liquid crystal elastic body 松下知识产权经营株式会社 2018-04-27 CN disclosed
CN-104460037-A Methods and apparatus for ophthalmic devices including cycloidally oriented liquid crystal layers JOHNSON & JOHNSON VISION CARE 2015-03-25 CN disclosed
EP-0903383-A1 Hot melt ink compositions Xerox Corporation (US) 1999-03-24 EP disclosed
US-5376302-A Having liquid crystal mixture containing dielectrically positive liquid crystalline, enantiotropic or monotropic two-ring compound to lower solubility in optically transparent polymer medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-12-27 US disclosed