Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450962 | 1.00 | MAOB (0.41) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8454135 | 0.95 | MAOB (0.45) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8454128 | 0.95 | MAOB (0.45) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8447383 | 0.92 | MAOB (0.41) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8447386 | 0.92 | MAOB (0.41) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8447398 | 0.90 | ESR2 (0.33) | MAOB | |
| SCHEMBL8447395 | 0.90 | ESR2 (0.33) | MAOB | |
| SCHEMBL8453568 | 0.90 | MAOB (0.40) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8453562 | 0.90 | MAOB (0.40) | MAOBCYP1A2CYP2A6TAAR1SLC6A2 | |
| SCHEMBL8452548 | 0.90 | MAOB (0.33) | MAOBTAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |