SCHEMBL8451

SCHEMBL8451

C#CCC[CH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8619 0.77
SCHEMBL129176 0.74
SCHEMBL141691 0.72 CYP1A2 (0.44)
SCHEMBL20503190 0.72 CYP1A2 (0.44)
SCHEMBL1275460 0.72 CYP1A2 (0.44)
SCHEMBL128011 0.72 CYP1A2 (0.44)
SCHEMBL1228396 0.72 CYP1A2 (0.44)
SCHEMBL20503206 0.72 CYP1A2 (0.44)
SCHEMBL1274555 0.72 CYP1A2 (0.44)
SCHEMBL128196 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 25895 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
US-20240207268-A1 PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-06-27 US claimed
US-20240199542-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2024-06-20 US claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-114450283-B 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents 法国施维雅药厂 2024-05-07 CN claimed
US-20240101759-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM RESONAC CORPORATION (JP) 2024-03-28 US claimed
US-11905274-B2 Receptor inhibitors, pharmaceutical compositions comprising the same and use thereof BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) 2024-02-20 US claimed
EP-4313053-A1 PYRAZOLYLPYRIMIDINES FOR TREATING MALIGNANT SOLID TUMOR Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) 2024-02-07 EP claimed
EP-4313943-A1 SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-02-07 EP claimed
WO-2023238906-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM 株式会社レゾナック 2023-12-14 WO claimed
EP-0305054-B1 IR-ray absorptive compound and optical recording medium by use thereof CANON KK (JP) 1994-03-30 EP claimed
EP-0180318-B1 AMIDE DERIVATIVES ICI AMERICAS INC. (US) 1991-11-06 EP claimed
US-4820836-A ANTICOAGULANTS, ANTIULCER AGENTS SHIONOGI & CO., LTD. (JP) 1989-04-11 US claimed
US-4745121-A AMINE OR CARBOXAMIDE SUBSTITUTED ICI AMERICAS INC. (US) 1988-05-17 US claimed
EP-0129928-B1 OXAZOLYL-SUBSTITUTED DIAZAHETEROCYCLES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-09-02 EP claimed
US-4648898-A DIAMINO-DIFLUOROMETHYLTHIOTRIAZINES SHIONOGI & CO., LTD. (JP) 1987-03-10 US claimed
EP-0180318-A1 Amide derivatives ICI AMERICAS INC. (US) 1986-05-07 EP claimed
EP-0129928-A1 Oxazolyl-substituted diazaheterocycles SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1985-01-02 EP claimed
US-4075006-A PESTICIDES, NEMATOCIDES, FUNGICIDES PPG INDUSTRIES, INC. (US) 1978-02-21 US claimed
US-4066440-A SYMMETRICAL ALKYNYL UREAS PPG INDUSTRIES, INC. (US) 1978-01-03 US claimed