SCHEMBL845109

SCHEMBL845109

CC=CC(=O)OCCC[Si](CCCOC(=O)C=CC)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.46
HCAR2 Q8TDS4 4/20 0.41
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 2/20 0.35
HPGD P15428 1/20 0.35
ALDH1A1 P00352 2/20 0.34
CYP3A4 P08684 1/20 0.34
GSTP1 P09211 1/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
APP P05067 4/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270109 0.94 ATM (0.49) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28569821 0.94 ATM (0.53) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1270259 0.92 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28415809 0.90 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL15015551 0.90 ATM (0.41) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL36569 0.86 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2672114 0.86 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL2141513 0.86 ATM (0.46) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL49180 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL66085 0.84 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211956-B2 Universal dental adhesion-promoter composition IVOCLAR VIVADENT AG (LI) 2012-07-03 US claimed
US-7256238-B2 Modified block copolymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2007-08-14 US claimed
US-20220171305-A1 EXTERNAL ADDITIVE PARTICLES, TONER, AND METHOD FOR PRODUCING EXTERNAL ADDITIVE PARTICLES CANON KABUSHIKI KAISHA (JP) 2022-06-02 US disclosed
US-20220128920-A1 EXTERNAL ADDITIVE PARTICLE AND TONER CANON KABUSHIKI KAISHA (JP) 2022-04-28 US disclosed
EP-2777687-B1 Dental primer formulation IVOCLAR VIVADENT AG (LI) 2018-11-07 EP disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-9974716-B2 Dental primer formulation IVOCLAR VIVADENT AG (LI) 2018-05-22 US disclosed
US-20180022913-A1 Block Copolymer Composition, Molded Material, Resin Composition, and Molded Product ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-01-25 US disclosed
EP-3257896-A1 BLOCK COPOLYMER COMPOSITION, MOLDING MATERIAL, RESIN COMPOSITION, AND MOLDED ARTICLE Asahi Kasei Kabushiki Kaisha (JP) 2017-12-20 EP disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-5670257-A HYDROLYZING AND CONDENSING ORGANOSILICON COMPOUND; HEAT TREATMENT; SPACERS FOR LIQUID CRYSTAL DISPLAY; NONFRACTURING NIPPON SHOKUBAI CO., LTD. (JP) 1997-09-23 US disclosed
US-5662961-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1997-09-02 US disclosed
EP-0767179-A2 Method for producing a rubber composition Bridgestone Corporation (JP) 1997-04-09 EP disclosed
US-5580619-A LIQUID CRYSTAL DISPLAY NIPPON SHOKUBAI CO., LTD. (JP) 1996-12-03 US disclosed
US-5520952-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1996-05-28 US disclosed
US-5503932-A SPACERS FOR LIQUID CRYSTAL DISPLAYS REQUIRING UNIFORM GAP DISTANCE BETWEEN MEMBERS; RESILIENCE NIPPON SHOKUBAI CO., LTD. (JP) 1996-04-02 US disclosed
EP-0653663-A1 Organic-inorganic composite particles and production process therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-05-17 EP disclosed
US-5204233-A Hydrophilic; silica or polymethyl methacrylate particles coated with a silane coupling agent KONICA CORPORATION (JP) 1993-04-20 US disclosed
US-4225663-A ABHESIVE LAYER CAPABLE OF REPELLING OLEO INK WHEN DRY; PHOTOBONDED TO IT IN IMAGE AREAS AN OLEO-INK RECEPTIVE LAYER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1980-09-30 US disclosed