Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8450354 | 1.00 | GRIA1 (0.36) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8451261 | 1.00 | GRIA1 (0.36) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8449532 | 0.95 | GRIA1 (0.34) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8449531 | 0.95 | GRIA1 (0.34) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8449535 | 0.95 | GRIA1 (0.34) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8454197 | 0.92 | GRIA1 (0.37) | GRIA1GRIA2GRIA3MAOBUSP30 | |
| SCHEMBL8454200 | 0.92 | GRIA1 (0.37) | GRIA1GRIA2GRIA3MAOBUSP30 | |
| SCHEMBL8454205 | 0.92 | GRIA1 (0.37) | GRIA1GRIA2GRIA3MAOBUSP30 | |
| SCHEMBL8449106 | 0.91 | ESR2 (0.38) | GRIA1GRIA2GRIA3ESR2CYP2C9 | |
| SCHEMBL8449111 | 0.91 | ESR2 (0.38) | GRIA1GRIA2GRIA3ESR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976408-A | Acrylonitrile derivative, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 1999-11-02 | — | — | US | disclosed |