Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451622 | 1.00 | SPHK1 (0.58) | SPHK1SPHK2KCNH2DRD2 | |
| SCHEMBL8453085 | 0.99 | SPHK1 (0.60) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8453079 | 0.99 | SPHK1 (0.60) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8447563 | 0.99 | SPHK1 (0.60) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8447559 | 0.99 | SPHK1 (0.60) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8447741 | 0.96 | SPHK1 (0.52) | SPHK1SPHK2DRD2 | |
| SCHEMBL8447738 | 0.96 | SPHK1 (0.52) | SPHK1SPHK2DRD2 | |
| SCHEMBL8447261 | 0.95 | SPHK1 (0.56) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8447264 | 0.95 | SPHK1 (0.56) | SPHK1SPHK2KCNH2 | |
| SCHEMBL8451950 | 0.94 | SPHK1 (0.58) | SPHK1SPHK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858275-A | Chlorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0785179-A1 | CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1997-07-23 | — | — | EP | disclosed |