SCHEMBL8451670

SCHEMBL8451670

CCC1CCC(CCC2CCC(c3ccc(-c4ccc(Cl)c(F)c4)cc3)CC2)CC1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.37
ESR2 Q92731 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP11B1 P15538 4/20 0.35
CYP11B2 P19099 4/20 0.35
OPRL1 P41146 5/20 0.35
FFAR1 O14842 1/20 0.34
DGAT1 O75907 2/20 0.34
SOAT1 P35610 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8451664 1.00 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8451661 1.00 CYP2C9 (0.37) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8453104 0.92 CYP2C9 (0.46) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8453098 0.92 CYP2C9 (0.46) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8453108 0.92 CYP2C9 (0.46) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL14525727 0.91 CYP2C9 (0.47) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8451125 0.90 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8451121 0.90 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8451119 0.90 CYP2C9 (0.39) CYP2C9ESR2ALDH1A1LMNAMAPT
SCHEMBL8452733 0.90 ESR2 (0.40) CYP2C9ESR2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5858275-A Chlorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0785179-A1 CHLOROBENZENE DERIVATIVE AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME CHISSO CORPORATION (JP) 1997-07-23 EP disclosed