Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CTSC | P53634 | 4/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5435908 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL1414979 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL14605825 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL5480201 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL497280 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL14052951 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL12408422 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL4550519 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL22418410 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 | |
| SCHEMBL8244065 | 1.00 | CYP2D6 (0.52) | CYP2D6LMNABLMALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724260-A1 | Process for the synthesis of ¬2S, 3aR, 7aS|-octahydroindole-2-carboxylic acid and its conversion to trandolapril | Sochinaz SA (CH) | 2006-11-22 | — | — | EP | disclosed |